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Others reported studies using AD mouse models fed a diet including deuterated 11,11-D 2 -linoleic acid ethyl ester (D 2 -LA) and 11,11,14,14-D 4 -alpha-linolenic acid ethyl ester (D 4 -ALA) in their diets for a sufficient period such that the phospholipids in brain became rich in deuterated fatty acids with allylic deuterium atoms in the indicated unsaturated fatty acids of phospholipids (127, 128)

This method has been used to extract polyphenols from green tea, laurel leaves, cannabis, and Phyllanthus emblica , with extracts showing anti-inflammatory and antioxidant activity (70, 71)

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Long-term ethanol feeding indirectly deactivated GPx4 through severe GSH exhaustion GPx4 is the only phospholipid hydroperoxide scavenger that protects cells from membrane disruption