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The combination of NNC with D-threo-PPMP (PPMP), a UDP-glucose ceramide glucosyltransferase(UGCG) inhibitor, further improved the antitumor activity of MAPKi in melanoma models [61]

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doi: 10.1007/s10495-025-02135-8, 99

thus sharing a key feature with MuSK MG (7779)

While that's substantially higher than the 600mg starting dose we generally favor for people new to NAC, it reflects the GlyNAC protocols studied in healthy-aging research.34 57 58 Some readers may prefer to start with a smaller serving for tolerability, but the clinical research on GlyNAC has generally evaluated gram-level doses of both ingredients, so it's unclear whether substantially lower amounts would provide the same benefits