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Yaralizadeh M et al

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When NNMT activity is dialed down, it allows for increased levels of nicotinamide adenine dinucleotide (NAD+), a coenzyme absolutely critical for countless metabolic processes, including energy production and cellular repair

Remarkably, subjects receiving pramlintide/metreleptin continued to lose weight until the end of the study, compared to those treated with pramlintide alone, whose weight loss had stabilized towards the end of the study