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TNF- may directly damage OLGs by forming peroxides of the long-chain fatty acids in lipids or via generation of ceramide which is cytotoxic to OLGs [47]

Similarly, as LC-FFA can exert different physiological effects on human -cells future studies should use a range of LC-FFA species within their investigations

This glial-driven inflammation can drive neuronal dysfunction and degeneration

doi: 10.1016/j.jhep.2019.08.026 Kim YJ, Tsang T, Anderson GR, Posimo JM, Brady DC ( 2020 )

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