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doi:10.1016/j.cvsm.2008.04.012

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In addition, previous studies have shown that morroniside has no toxicity in various cell types and no obvious adverse effects in animals 37,39

Thus, the consequent noxious occlusion-like syndrome, occlusion syndrome and multiple organ failure was peripherally and centrally avoided [13,14,15,16,20,22,23,24,25], despite the permanent occlusion of the bile duct