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Research demonstrates it upregulates growth hormone receptors locally, promotes angiogenesis through VEGF pathways, and modulates nitric oxide synthesis to accelerate tissue vascularization

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It is important to note that BDNF levels in the serum and tears of glaucoma patients are significantly lower than in control subjects, suggesting that deficits in this neurotrophin may participate in RGC death in glaucoma (Oddone et al., 2017)