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For example, the use of prebiotics, probiotics, or their metabolites that promote SCFA production has been shown to improve gut microbiota, enhance barrier function, and regulate inflammatory responses [438, 446]

Increased oxidative damage in the lungs and poor antioxidant protection, including low levels of CoQ10, can result in lung diseases like asthma and chronic obstructive pulmonary disease (COPD) ( Furthermore, it has been shown that people suffering from these conditions present lower levels of CoQ10 ( A study demonstrated that supplementing with CoQ10 reduced inflammation in individuals who had asthma, as well as their need for steroid medications to treat it ( Another study showed improvements in exercise performance in those suffering from COPD

56 SAM is also a critical methyl donor for histone methylation

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