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Key selection factors for Sri Lanka include heat-stable formulations (due to tropical climate) and CDDRA-compliant ingredient lists

For instance, MMP-3 promotes EMT by activating Wnt/-catenin and TGF- signaling pathways, while simultaneously inducing fibroblast proliferation and collagen deposition, as demonstrated by reduced fibrosis in MMP-3-knockout mice following bleomycin challenge (Pardo et al., 2016

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Meanwhile, studies have reported that 2,2-Bipyridine exerts ferroptosis inhibition by chelating intra-mitochondrial iron ( 1,10-Phenanthroline resembles and downregulates mitochondrial ROS accumulation and inhibits ferroptosis induced by zero-valent iron nanoparticles in vitro with 2,2-Bipyridine (Huang et al., 2019

Nature (2002) 418:1915.10.1038/nature00858 36 DumitriuIEBaruahPValentinisBVollREHerrmannMNawrothPPet alRelease of high mobility group box 1 by dendritic cells controls T cell activation via the receptor for advanced glycation end products

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