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Key areas of interest include: Cell proliferation and differentiation in multiple tissue types Muscle biology , including satellite cell behavior and myostatin-related pathways Metabolic signaling , particularly IGF-1R and insulin receptor cross-talk Tissue maintenance and repair models in long-term aging and glucocorticoid-exposure paradigms By offering a prolonged IGF-1like signal, IGF-1 LR3 enables researchers to investigate sustained pathway activation and long-term cellular responses in a more controlled way than with short-lived native IGF-1

10.1016/j.jare.2020.07.007 221 WangZ.-K.ChenR.-R.LiJ.-H.ChenJ.-Y.LiW.NiuX.-L.et al (2020b)

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HBV model systems are required to identify new potential therapeutic agents

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