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In a healthy situation, the ECM proteoglycans such as aggrecan, inherently inhibit neurite growth

Bibcode:2013NTxT...36...47R

J Affect Disord 113:28590 Godman CA, Chheda KP, Hightower LE, Perdrizet G, Shin DG, Giardina C (2010) Hyperbaric oxygen induces a cytoprotective and angiogenic response in human microvascular endothelial cells