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Fatty acid oxidation In diet-induced obese mice and ob/ob mice, 50 mg/kg twice daily for 28 days increased whole-body energy expenditure and fatty acid oxidation, reduced fat mass, lowered cholesterol and triglycerides, and improved insulin sensitivity without changing food intake

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There were a lot of powerlifters inside these studies, so they typically have a lot of knee pain, and thats the first reported thing, and then back pain is second