glutathione peroxidase type 2 4‐dependent glutathione high‐consumption drives acquired platinum chemoresistance in lung cancer‐derived brain metastasis - Liu - 2021 - Clinical and Translational Medicine Trait: Oxidative Stress Risk (GPx-1)

On a regular basis the following process is completed to produce daily needed amounts of glutathione: The process of glutathione production is known as the gamma-glutamyl cycle

All patients had HBV RNA levels declines 2 log 10 IU/mL and all were below the limit of detection

Glutamine metabolism in breast cancer and possible therapeutic targets

The profound exhaustion, cognitive impairment often described as "brain fog," and unpredictable crashes can make simply getting through the day feel like running a marathon

1878-A INDIVIDUALIZED HCV TREATMENT FOR PWIDS ON OPIOID AGONIST THERAPY LED TO EXCELLENT ADHERENCE THROUGHOUT THE COVID19 PANDEMIC Caroline Schwarz 1,2 , Angelika Schtz 3 , Raphael Schubert 3 , Michael Schwarz 2 , Anika Jenke 3 , David Josef Maria Bauer 1,2 , Lukas Burghart 1,2 , Benjamin Steinwender 3 , Enisa Gutic 1 , Thomas Reiberger 2,4 , Hans Haltmayer 3 and Michael Gschwantler 1,5 , (1)Klinik Ottakring, (2)Medical University of Vienna, (3)Suchthilfe Wien Ggmbh, (4)Cemm Research Center for Molecular Medicine of the Austrian Academy of Sciences, (5)Sigmund Freud University Background: Directly observed therapy (DOT) with DAAs (direct-acting antivirals) is successful in eliminating HCV in PWIDs (people who inject drugs) on opioid agonist therapy (OAT): DAAs are prescribed via a low-threshold facility (LTF), and supervised DAA administration alongside OAT is performed at a pharmacy or LTF

Chung, Massachusetts General Hospital and Harvard Medical School Background : Hepatic stellate cell (HSC) and Kupffer cell activation are accompanied by increased expression of chemokines and chemokine receptors, including CC-chemokine receptor 2 (CCR2)