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Low Vitamin B12 levels are more common in vegetarians, vegans, and older adults

This commenter further noted that the substantial clinical improvement criterion should be applied rigorously and that innovations should earn supplemental payment only if they offer a real patient-care advantage, not merely convenience

In one key example, Hunter et al

The performance and financial cost of extended absence create motivation to explore off-label options despite regulatory and safety uncertainties

By supporting the production of healthy red blood cells, B12 injections can also help prevent or treat megaloblastic anemia - a condition where red blood cells are too large and unable to carry oxygen efficiently