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Supplementary material The Supplementary Material for this article can be found online at: References 1 BrazeauPValeWBurgusRLingNButcherMRivierJet al

Important Considerations: Professional Guidance: Glutathione cocktails are potent formulations that should only be administered by qualified professionals

It should be mixed with 200 ml of saline water and given as an IV drip for 30 minutes once a week

Ongoing trials for FUS are evaluating whether BBB disruption with FUS can improve the effects of systemic chemotherapy (NCT03712293 and NCT03551249) or radiotherapy (NCT04988750)