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This result led to a recent, larger randomized controlled trial that has been completed by our group at the University of California, San Francisco, and initial (unpublished) results suggest that B12 is also effective in improving overall symptoms

*Correspondence: Ashraf Albrakati, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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This unique biodistribution profile enables selective antioxidant activity, mitochondrial modulation, and anti-inflammatory signaling, conferring therapeutic potential particularly for neurological disorders, ischemia-reperfusion injuries, and chronic pain syndromes

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