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Nausea and constipationthe most common side effectstend to peak 24 to 48 hours after injection for most patients

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Inflammation haptocorrin levels can increase due to granulocyte activation or as an acute phase response Decreased clearance: Renal failure decreased clearance of transcobalaminB12 complexes Mechanism: Most elevated B12 is not free or biologically active , but rather bound to haptocorrin , which has a long half-life and is increased in certain diseases

one located on the 30S subunit and three on the 50S subunit

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