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Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX), a producer of reactive oxygen species (ROS), acts as a key generator of oxidative stress within pancreatic islet -cells, significantly affecting glucose-induced insulin release and -cell viability in Type 1 and Type 2 diabetes (Marta et al., 2010)

Mycotoxins are small, lipophilic molecules that accumulate in body fat, disrupt immune function, impair mitochondrial energy production and cross the blood-brain barrier

At night, there is increase in the production of cytokines which increases inflammation whereas production of corticosteroids which reduce inflammation is decreased