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Finally, we emphasize the indispensable role of advanced human models, such as human pluripotent stem cell-derived islets

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IV administration might be chosen if you are already on IV fluids or need a very rapid correction of vitamin levels

Specifically, it produces no IGF-1 elevation (avoiding proliferative concerns), no negative impact on glucose metabolism (avoiding diabetes risk), no fluid retention or edema, and no concerning patterns of joint pain that can occur with growth hormone

The compounded pharmacy version wasnt perfect, but it was a significantly cleaner situation than whats left on the table