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Hence, our objective was to alleviate the local hypoxic condition by degrading H 2 O 2 in situ to generate oxygen (O 2 )

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This was evidenced by RBC Prdx2 in G6PD-deficient infants, with a higher proportion shown to maintain the oxidized state and are poorly reactivated after peroxide challenge (20)

[PubMed] [Google Scholar] Jardieu P, Clark R, Mortensen D, Dorshkind K

Research applications Research applications In vitro assays of ECM regulation (collagen, elastin) and MMP/TIMP balance Cell migration, proliferation, and cellular migration and tissue-matrix development models (fibroblasts, keratinocytes) Anti-inflammatory and antioxidant signaling studies (NF-B, Nrf2 pathways) Copper-dependent enzymatic and metalloregulator investigations Mechanistic combination studies with growth factors, cytokines, or small molecules For laboratory research use only