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doi:10.1073/pnas.0510836103

Several years after the initial observation of Tsui et al., -arrestin was found to function as a scaffold for both TSHR and IGF-IR (122), This association potentially accounts for protein:protein crosstalk as underlying the apparent importance of IGF-IR activity in TSHR signaling

Think of it as lighting a fire rather than being the fuel

If you start very aggressively, have significant overgrowth, or sluggish detox pathways, symptoms can last up to two weeks

Plant J Transcriptomic and metabolomic analyses unveil TaASMT3-mediated wheat resistance against stripe rust by promoting melatonin biosynthesis