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Currently, studies only evaluate the development of airway remodeling, such as through CT scans, and correlate it with asthma severity (134) or lung function and risk of exacerbation (135), but the correlation with markers of systemic inflammation remains limited

[0433] The procedure for attaching an effector to an antibody will vary according to the chemical structure of the effector and/or antibody

Bulk microarray comparison between these two organoid types was performed in our previous study 14 , confirming that this system effectively captures the transcriptional features of homeostatic epithelium containing CBCs and of repair-phase epithelium expressing strong revSC signatures

Sections were heated in citrate buffer (pH 6.0) for 10 min for antigen retrieval and incubated in 1% bovine serum albumin (BSA) dissolved in PBS at 37 C for 20 min to prevent nonspecific background staining

That said, combining injectable and topical approaches creates a two-pronged strategy that addresses skin from both the inside out and the outside in

Most clinical studies showing positive results used doses within this range over 8-12 week periods