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Novel potential mechanisms of acquired resistance to anti-EGFR monoclonal antibody (mAb) therapy detected in liquid biopsies (LBx) from patients (pts) with advanced colorectal cancer (CRC)

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To further validate our model, we compared the residence probability (the probability for the system to remain in a certain microstate) as a function of time obtained from the propagation of the MSM with those from the original MD trajectories 41 (Supplementary Fig

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Buzza MS, Netzel-Arnett S, Shea-Donohue T, Zhao A, Lin CY, List K, Szabo R, Fasano A, Bugge TH, Antalis TM