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Moreover, the expression of the regulatory subunit MAT2B is frequently linked to the increase in MAT2A, conferring growth advantage to liver cancer cells [61,121,123,240] and potentially serving as biomarkers

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Even the gold standard anti-ferroptotic drug liproxstatin, previously thought to exclusively exert protection via directly trapping free radicals [17] , has recently been shown to prevent ferroptosis by inactivating iron in the lysosome [18]