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Description

Oxidative stress as a common key event in developmental neurotoxicity

b Data from a subgroup of trial participants: 44, 24, and 20 patients allocated to ALC and 46, 20, and 26 patients allocated to placebo when considered as a whole (overall) and over statin YES and statin NO stratifications, respectively

The second strategy emphasizes the use of advanced delivery platformsincluding engineered exosomes and lipid nanoparticlesto improve CNS drug targeting

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It has also been shown that ferroptosis causes marked morphological changes to mitochondria, such as shrinking, cristae disappearance, disruption of OMM, and increased bilayer membrane density [234, 235]