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Biomedicines 8 , 284 (2020)

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Modeling of TREX1-dependent autoimmune disease using human stem cells highlights L1 accumulation as a source of neuroinflammation

In this context, DMF promotes Th2 cell differentiation, with immunoregulatory functions ( In summary, the rationale of employing DMF in psoriasis consists in reducing cellular inflammation both by decreasing glutathione intracellular levels and by inducing a switch in immune response toward an anti-inflammatory/immunoregulatory setting ( The Role of Small Molecules in the Metabolic Syndrome Patients with psoriasis are characterized by a higher prevalence of cardiovascular disease and metabolic syndrome ( Funding This study received funding from Almirall S.p.A

Iwatsubo, T et al., Pharmacol Ther 1997, 73, p