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Structurally, calretinin is a calcium-binding protein which contains 6 EF-hand domains, four of them bind to Ca 2+ with high affinity, one is not binding to Ca 2+ , while one was non-functional and without Ca 2+ binding affinity (46,47)

& Chatzinikolaidou, M

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Although less common in this form than cyanocobalamine and methylcobalamine, hydroxocobalamine is also available as pills for oral or sublingual administration