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Moreover, N-glycosylation of SREBP cleavage-activating protein (SCAP) is essential for Golgi localization and activation of SREBP once EGFR induced glucose uptake in glioblastoma multiforme (GBM) (Cheng et al., 2015, 2016)

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doi: 10.3389/fphar.2026.1795174 Received 24 January 2026 Revised 09 April 2026 Accepted 13 April 2026 Published 30 April 2026 Volume 17 - 2026 Edited by Nabil Eid, IMU University, Malaysia Reviewed by MoezAlIslam Ezzat Faris, Applied Science Private University, Jordan Payal Bhatnagar, International Medical University, Malaysia Gehan El Akabawy, Ajman University, United Arab Emirates Updates Copyright 2026 Ma, Hao, Wang, Qiu, Cao, Deng, Wang, Li, Zhang, Wei, Yao, Gao, Yi, Liu and Li

Cell Stem Cell 11 , 783798 (2012)

The central nervous system is rich in lipids, ROS can oxidize polyunsaturated fatty acids easily, and IH induces the increase of ROS and the imbalance of the oxidation-antioxidant system [24, 35, 75]

Decrease dietary and environmental toxin exposure, from pollution, pesticides, smoked foods, heavy metals and nitrates used as a food preservative