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Franco R, DeHaven WI, Sifre M, Bortner CD, Cidlowski JA

Complete loss of GPX4 is incompatible with viability, and pharmacological or genetic GPX4 inhibition is widely exploited to induce ferroptosis in cells and tissues

[DOI] [PubMed] [Google Scholar] 48.Hayakawa M., Miyashita H., Sakamoto I., Kitagawa M., Tanaka H., Yasuda H., Karin M., Kikugawa K

Upon amino acid/nutrient abundance, the mTORC1-dependent phosphorylation of Atg14-containing Vps34 complex inhibits the autophagosome biogenesis and suppresses autophagy

Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo

Oxidized glutathione was recycled into reduced glutathione by glutathione reductase and -nicotinamide adenine dinucleotide phosphate (NADPH)