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Furthermore, there is increased variability of viral cellular tropism with the emergent SARS-CoV-2 variants, which include Alpha, Beta, Gamma, Epsilon, Eta, Iota, Kappa, 1.617.3, Mu, Zeta, and in particular, Delta and Omicron, as well as the various lineages of each variant [14]

This process triggered SLC7A11 degradation, intensifying oxidative stress and resulting in ferroptosis [127]

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Another feature of aging related to cellular accumulation of reactive oxygen species and mitochondrial dysfunction is cognitive decline

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