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General antioxidants, some of which exhibit ferroptosis inhibition in vitro , have also been evaluated clinically but with limited efficacy (Table 2)

For GLP-1 agonists, periodic pancreatic enzyme levels (lipase, amylase) provide early warning of potential pancreatic issues

In the future, prolonged monitoring of GABA and GABA/Glx would be helpful to illustrate this dynamic change of these neurotransmitters during the GABA switch associated with the neurodevelopment and bumetanide treatment

GHK-Cu occurs naturally in the human body and decreases with age

Here, we summarize the features, process, function, and mechanisms of ferroptosis, discuss its relevance with oxidative stress and cellular inflammation linking to cardiovascular disorders, raise the unsolved mysteries of ferroptosis, and provide new insights to consider the ferroptosis as the therapeutic target for the prevention and treatment of CVDs