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M2 receptors, a Gi-coupled type of receptors, are the most represented at the cardiac level and their activation reduces cAMP concentration and activates the G protein-coupled inwardly rectifying potassium channels (GIRK) channels (Bywater et al

Transport and positioning of mitochondria are essential for neuronal homeostasis and the mitochondrial movement is a part of regulation by intracellular signals

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Oxidative stress plays a preponderant, key role in the pathogenesis of MS