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In the general population, vitamin B12 deficiency affects: About 3% of people aged 20 to 40 Up to 20% of those aged 85 and older However, studies suggest that 30% to 50% of individuals who have undergone surgeries involving the removal of the terminal ileum or colon may develop B12 deficiency, up to 15 times higher than the general population

In February 2026, approximately 14 peptides returned to Category 1 compounding status after being restricted in late 2023

2017 Dec;164(2):140-143

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