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Striking a NRF2: the rusty and rancid vulnerabilities toward ferroptosis in Alzheimers disease

Accumulation of lipid peroxides drives ferroptosis Polyunsaturated fatty acids (PUFAs) containing bis -allylic carbons are highly susceptible to lipid peroxidation [37], and recent findings suggest that a wide range of PUFAs may be involved in the ferroptosis pathway [15]

doi: 10.1146/annurev.physiol.69.031905.164337 20 ZhangDLGhoshMCRouaultTA

Maintenance phase After the target serum ferritin level has been achieved, the maintenance phase commences to stabilise the level

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