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The patient had improvement of his motor symptoms to BFCRS of 4 and he was medically cleared

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In addition to HMGCR, the MVA pathway genes HMGCoAS1, GGPS1, SCAP, and SREBP2 are also good candidates to either suppressing other enzymes in the MVA pathway or blocking the SREBP-mediated feedback response in combination with statin therapy (207)