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In case of long-term treatment, it is possible to reduce the dose of the drug (600 mg or 300 mg), which can be administered intramuscularly or slowly intravenously

Further research involving more drugs is necessary to determine optimal concentrations and assess their safety and effectiveness comprehensively

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The commenter claimed that CMS made a similar decision when it rejected the CANARY Canturio TM Tibial Extension (CTE) with CHIRP System application in the CY 2025 OPPS/ASC proposed rule after concluding that the CTE implant within the CHIRP system was not integral to the arthroplasty procedure identified in the application

Luo, Z., Wang, S

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