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Mutating H95 affected the ability of Affimer K3 to immunoprecipitate KRAS, with mutation to glutamine (as found in HRAS) reducing the amount of RAS pulled down by 45% and mutation to a hydrophobic leucine residue (as found in NRAS) abolishing RAS immunoprecipitation completely thus giving support to our previous observations (Fig

Decyanation of vitamin B12 by a trafficking chaperone

Rotating sites consistently prevents the tissue trauma that contributes to reactions

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Thus, NASO B12 is found to be effective in treating the deficiency of vitamin B12 in type 2 diabetes mellitus patients on metformin therapy