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However, translation to clinical practice remains hindered by several limitations, such as species-specific differences in experimental models, small and heterogeneous patient makeup in clinical studies, and an incomplete understanding of the multifactorial nature of IRI

Ralston or another member of his team will inject the pre-specified neuromodulator directly into the patients treatment area

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

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If you experience worsening fatigue, jaundice (yellowing of skin or eyes), abdominal swelling, or confusion, contact your GP urgently, as these may indicate progression of liver disease requiring medical assessment