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Similarly, oral acute toxicity tests at 3,000 mg/kg and 5,000 mg/kg resulted in no deaths, suggesting an LD 50 greater than 5,000 mg/kg, classifying it as practically non-toxic and safe (709)

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1 Contrary to normal cells, cancer cells are characterized by significantly increased levels of ROS owing to their unrestrained growth and increased metabolism

L-arginine can induce a shift from glycolysis to OXPHOS in effector T cells, enhancing their anti-tumor immune effects

Zimmermann, C