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GSTs as housekeepers catalyze the glutathione (GSH) conjugating to some electrophilic compounds [27], thus determining its classic role in the detoxification of exogenous substances such as anti-cancer drugs [28]

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Substantial morbidity and mortality have been reported to be associated with infection [15, 17, 42]

The fat-redistribution effect on visceral adipose tissue becomes detectable on abdominal CT scans after approximately 8 weeks and plateaus between 26 and 52 weeks of continuous administration

Consent for publication All study participants consented to publication of their anonymised data