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However, chitin, which is a polymer that confers structural rigidity to fungi, helminths, crustaceans, and insects, induces accumulation of eosinophils in tissues through production of LT B4 in mice.48 Eosinophils also are activated by fungal organisms that release proteases, such as Alternaria , through protease-activated receptors (PARs)

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To realize this vision, biomarker development must evolve beyond simple antigen expression

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