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The use of EGCG as a component of the nanoparticle itself to encapsulate curcumin, rather than just a co-administered agent, represents a sophisticated approach to drug delivery and synergistic action

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Fluorescence imaging is still considered the most used imaging tool to visualize cellular interaction of PLGA and other polymeric nanoparticle and has been recently extended to monitor their biodistribution in vivo 5

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Lipid-based nanoparticles as drug delivery systems for cancer immunotherapy

However, cases of concomitant deficiencies involving B 12 with either B 1 or B 6 remain rare, suggesting distinct risk factors and clinical presentations for each vitamin deficiency