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doi:10.1515/jcim-2014-0058

Tumors can also hijack DC maturation to decrease MHC expression and destroy the costimulatory machinery by secreting suppressive factors such as TGF-, interleukin-10 (IL-10), and vascular endothelial growth factor (VEGF) [110]

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Acrolein inhibited the production of proinflammatory cytokines with an IC 50 of 3 M, which could be physiologically relevant in view of the amounts of acrolein generated by a single cigarette (60 g = 1.1 mol)

[00027] "Optional" or "optionally" as used herein means that the subsequently described event or circumstance can or cannot occur, and that the description includes instances where the event or circumstance occurs and instances where it does not