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doi: 10.3389/fphar.2025.1714859 Received 29 September 2025 Revised 02 November 2025 Accepted 10 November 2025 Published 28 November 2025 Volume 16 - 2025 Edited by Wei Chen, Gan and Lee Pharmaceuticals, China Reviewed by Limin Shi, Johns Hopkins All Childrens Hospital, United States Peng Wang, Nanjing Drum Tower Hospital, China Dongmei Wang, Chinese Academy of Medical Sciences and Peking Union Medical College, China Updates Copyright 2025 Zhang, Yang, Yang, Sun, Chen, Zhang and Liu