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10.1016/j.bcp.2007.11.012 66 RajhardS.HladnikL.VicenteF

3.2 Mechanism of NLRP3 inflammasome activation Currently, NLRP3 inflammasome activation pathways are broadly categorized into canonical, noncanonical, and alternative pathways (Figure 1), with classification criteria predicated on stimulus specificity (e.g., PAMP vs