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Acetylation of p53 at K320 activates CDKN1A/p21, thereby delaying ferroptosis (Abbas and Dutta, 2009

Additionally, rare loss-of-function germline mutations of Kelch-like ECH-associated protein 1 (KEAP1) could be detected in nodular goitre leading to Nrf2 pathway activation that favours transcription of cytoprotective and antioxidant enzymes (92)