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L-arginine supplementation has also been explored for its potential to improve exercise tolerance in individuals with cardiovascular conditions

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Antioxidant enzymes like catalase, glutathione peroxidase, and superoxide dismutase (SOD) play a crucial role in cellular defense by converting free radicals into less harmful molecules

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caffeine in large amounts (usually 3 cups or more)

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PSII can also contribute when electron flow is disrupted (Murata et al., 2007)

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For persistent dark circles, professional treatments may be more effective

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The signaling pathways involved mainly include caspase-induced apoptosis pathway, PI3K-Akt signaling pathway, NF-B signaling pathway, etc (Figure 3)

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