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Serum homogenate was centrifuged at 21,000 g for 5 minutes at 4 C

Clinical features of withdrawal headache following overuse of triptans and other headache drugs

[DOI] [PMC free article] [PubMed] [Google Scholar] [346].Zheng X, Yoo MJ, Hage DS, Analysis of free fractions for chiral drugs using ultrafast extraction and multi-dimensional high-performance affinity chromatography, Analyst 138 (2013) 62626265

Riboflavin deficiency is prevalent in many regions over the world, particularly in underdeveloped countries with a low intake of dairy products and meats 5,6,7,8

In recent work, Lopes and colleagues demonstrated that caffeine increased the energy charge and redox state of cortical synaptosomes, suggesting that this effect led to an increase in the glycolytic rate, thereby enhancing astrocyte-synapse lactate transport