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Its classification has been the subject of some debate and histopathologic findings do not always completely resolve clinical uncertainties as they can be indicative of both dysplastic nevus and melanoma.4,810 Clinically, atypical lentiginous nevus manifests as a pigmented lesion located in an area of chronic sun damageprimarily on the back or the proximal parts of the limbsin individuals aged 50 to 70 years

This is especially important when treating areas where preserving cosmetic appearance and function is crucial, such as the face, eyelids, nose, lips, ears, and hands

When checking for skin cancer, be sure to look under the feet and at the palms of your hands, have a loved one check your scalp, and remember to look in between fingers and toes

Immunohistochemical analysis revealed strong cytoplasmic immunoreactivity of dendritic melanocytes for proteinS-100, HMB-45 and melan-A.Positive staining for proliferative markers (MCM-2, MCM-5, Ki-67) was only observed in basal and suprabasal epithelial cells, confirming the reactive etiology of the lesion

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Choose a sunscreen with minimum SPF (Sun Protection Factor) of 30 with protection from both UVA and UVB rays