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For example, one study developed a prognostic model based on ferroptosis-related genes using RNA-seq data from NSCLC patients, revealing that patients in the high-risk group had significantly lower overall survival compared to those in the low-risk group ( These findings indicate that ferroptosis-related genes not only play a pivotal role in the initiation and progression of lung cancer but also have potential clinical applications, providing a foundation for the development of personalized treatment strategies

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Drouin J, Trifiro MA, Plante RK, Nemer M, Eriksson P, Wrange O

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Autophagy 14 , 181189 (2018)