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Multiple transport mechanisms involved in the intestinal absorption of metformin: impact on the nonlinear absorption kinetics

Thioredoxin peroxidase, a selenium-dependent enzyme, also has an important role in the elimination of hydrogen peroxide (Lu and Holmgren, Figure 7 Recently, hydrogen peroxide has been shown to use water channels, the aquaporins, to cross the lipid membrane more rapidly than diffusion allows (Bienert et al., 1995b)

Health Place 12(2):203209

doi: 10.1186/s12964-019-0405-8 126 JiangHKhanSWangYCharronGHeBSebastianCet al

Keshavan), R24 GM078233 (Rima Kaddurah-Daouk), c UL1 RR024153 and NIH/NCRR/GCRC Grant M01 RR00056], Metabolomics Research Network (Rima Kaddurah-Daouk)